Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques

The ALVAC prime/ALVAC + AIDSVAX B/E boost RV144 vaccine trial induced an estimated 31% efficacy in a low-risk cohort where HIV‑1 exposures were likely at mucosal surfaces. An immune correlates study demonstrated that antibodies targeting the V2 region and in a secondary analysis antibody-dependent c...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Luo, Kan, Liao, Hua-Xin, Zhang, Ruijun, Easterhoff, David, Wiehe, Kevin, Gurley, Thaddeus C., Armand, Lawrence C., Allen, Ashley A., Von Holle, Tarra A., Marshall, Dawn J., Whitesides, John F., Pritchett, Jamie, Foulger, Andrew, Hernandez, Giovanna, Parks, Robert, Lloyd, Krissey E., Stolarchuk, Christina, Sawant, Sheetal, Peel, Jessica, Yates, Nicole L., Dunford, Erika, Arora, Sabrina, Wang, Amy, Bowman, Cindy M., Sutherland, Laura L., Scearce, Richard M., Xia, Shi-Mao, Bonsignori, Mattia, Pollara, Justin, Edwards, R. Whitney, Santra, Sampa, Letvin, Norman L., Tartaglia, James, Francis, Donald, Sinangil, Faruk, Lee, Carter, Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-ngarm, Supachai, Michael, Nelson L., Kim, Jerome H., Alam, S. Munir, Vandergrift, Nathan A., Ferrari, Guido, Montefiori, David C., Tomaras, Georgia D., Haynes, Barton F., Moody, M. Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135278/
https://ncbi.nlm.nih.gov/pubmed/27942585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88522
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