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Highly Efficient Generation of Human Hepatocyte–like Cells from Induced Pluripotent Stem Cells

There exists a worldwide shortage of donor livers available for orthotropic liver transplant (OLT) and hepatocyte transplantation therapies. In addition to their therapeutic potential, primary human hepatocytes facilitate the study of molecular and genetic aspects of human hepatic disease and develo...

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Main Authors: Si-Tayeb, Karim, Noto, Fallon K., Nagaoka, Masato, Li, Jixuan, Battle, Michele A., Duris, Christine, North, Paula E., Dalton, Stephen, Duncan, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946078/
https://ncbi.nlm.nih.gov/pubmed/19998274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23354
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