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‘JD’ iPS cell–derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia
Elevated levels of low density lipoprotein cholesterol (LDL-C) in plasma are a major contributor to cardiovascular disease (CVD), which is the leading cause of death worldwide. Genome–wide association studies (GWAS) have identified 95 loci that associate with control of lipid/cholesterol metabolism....
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900031/ https://ncbi.nlm.nih.gov/pubmed/22653811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25871 |
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