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Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo

BACKGROUND: RhoA and RhoC have been proved to be over-expressed in many solid cancers, including colorectal cancer. The reduction of RhoA and RhoC expression by RNA interference (RNAi) resulted growth inhibition of cancer cells. The present study was to evaluate the effect of silencing of RhoA and R...

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Bibliografiske detaljer
Main Authors: Wang, Haibo, Zhao, Gang, Liu, Xiangping, Sui, Aihua, Yang, Kun, Yao, Ruyong, Wang, Zongbao, Shi, Qiang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945978/
https://ncbi.nlm.nih.gov/pubmed/20828398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-123
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