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Inhibitory effects of adenovirus mediated tandem expression of RhoA and RhoC shRNAs in HCT116 cells

BACKGROUND: RhoA and RhoC are deregulated by over expression in many human tumors, including colorectal cancer. Some reports show that they play a pivotal role in the carcinogenesis, tumor development and infiltration metastasis. In this study, for the first time we constructed recombinant adenoviru...

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Autores principales: Liu, Xiang-ping, Wang, Hai-bo, Yang, Kun, Sui, Ai-hua, Shi, Qiang, Qu, Shen
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672922/
https://ncbi.nlm.nih.gov/pubmed/19374769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-28-52
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