Ric-3 Promotes α7 Nicotinic Receptor Assembly and Trafficking through the ER Subcompartment of Dendrites

The function of Ric-3, which is required for nicotinic acetylcholine receptor (nAChR) expression in C. elegans, is unclear. Here we found that Ric-3 can promote or inhibit cell-surface delivery of α-bungarotoxin-binding nAChRs (BgtRs) composed of α7 subunits. At low levels, Ric-3 promoted BgtR assem...

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Hauptverfasser: Alexander, John K., Sagher, Daphna, Krivoshein, Arcadius V., Criado, Manuel, Jefford, Gregory, Green, William N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945888/
https://ncbi.nlm.nih.gov/pubmed/20668195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6344-09.2010
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