VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

The cellular and molecular mechanisms by which a tumour cell undergoes metastasis to a predetermined location are largely unknown. Here we demonstrate that bone marrow-derived haematopoietic progenitor cells that express vascular endothelial growth factor receptor 1 (VEGFR1; also known as Flt1) home...

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主要な著者: Kaplan, Rosandra N., Riba, Rebecca D., Zacharoulis, Stergios, Bramley, Anna H., Vincent, Loïc, Costa, Carla, MacDonald, Daniel D., Jin, David K., Shido, Koji, Kerns, Scott A., Zhu, Zhenping, Hicklin, Daniel, Wu, Yan, Port, Jeffrey L., Altorki, Nasser, Port, Elisa R., Ruggero, Davide, Shmelkov, Sergey V., Jensen, Kristian K., Rafii, Shahin, Lyden, David
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945882/
https://ncbi.nlm.nih.gov/pubmed/16341007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04186
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