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S100 chemokines mediate bookmarking of premetastatic niches
Primary tumours release soluble factors, including VEGF-A, TGFβ and TNFα, which induce expression of the chemokines S100A8 and S100A9 in the myeloid and endothelial cells within the lung before tumour metastasis. These chemokine-activated premetastatic niches support adhesion and invasion of dissemi...
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Auteurs principaux: | , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2006
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2955889/ https://ncbi.nlm.nih.gov/pubmed/17139281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1206-1321 |
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