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S100 chemokines mediate bookmarking of premetastatic niches

Primary tumours release soluble factors, including VEGF-A, TGFβ and TNFα, which induce expression of the chemokines S100A8 and S100A9 in the myeloid and endothelial cells within the lung before tumour metastasis. These chemokine-activated premetastatic niches support adhesion and invasion of dissemi...

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Autors principals: Rafii, Shahin, Lyden, David
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955889/
https://ncbi.nlm.nih.gov/pubmed/17139281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1206-1321
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