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Extending the PRIME Model for Protein Aggregation to All Twenty Amino Acids

We extend PRIME, an intermediate-resolution protein model previously used in simulations of the aggregation of polyalanine and polyglutamine, to the description of the geometry and energetics of peptides containing all twenty amino acid residues. The 20 amino acid side chains are classified into 14...

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Autores principales: Cheon, Mookyung, Chang, Iksoo, Hall, Carol K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945877/
https://ncbi.nlm.nih.gov/pubmed/20740494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22817
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