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Mechanism of the Enantioselective Oxidation of Racemic Secondary Alcohols Catalyzed by Chiral Mn(III)–Salen Complexes

The experiments described here clarify the mechanism and origin of the enantioselectivity of the oxidation of racemic secondary alcohols catalyzed by chiral Mn(III)–salen complexes using HOBr, Br(2)/H(2)O/KOAc or PhI(OAc)(2)/H(2)O/KBr as a stoichiometric oxidant. Key points of the proposed pathway i...

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Bibliographic Details
Main Authors: Brown, M. Kevin, Blewett, Megan M., Colombe, James R., Corey, E. J.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945693/
https://ncbi.nlm.nih.gov/pubmed/20666410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103103d
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