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Nonhomologous DNA End Joining in Cell-Free Extracts

Among various DNA damages, double-strand breaks (DSBs) are considered as most deleterious, as they may lead to chromosomal rearrangements and cancer when unrepaired. Nonhomologous DNA end joining (NHEJ) is one of the major DSB repair pathways in higher organisms. A large number of studies on NHEJ ar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sharma, Sheetal, Raghavan, Sathees C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE-Hindawi Access to Research 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945661/
https://ncbi.nlm.nih.gov/pubmed/20936167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/389129
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