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‘Click’ Reaction in Conjunction with Diazeniumdiolate Chemistry: Developing High-Load Nitric Oxide Donors
[Image: see text] The use of Cu(I)-catalyzed ‘click’ reactions of alkyne-substituted diazeniumdiolate prodrugs with bis- and tetrakisazido compounds is described. The ‘click’ reaction for the bis-azide using CuSO(4)/Na-ascorbate predominantly gave the expected bis-triazole. However, CuI/diisopropyle...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945422/ https://ncbi.nlm.nih.gov/pubmed/20812718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101645k |
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