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‘Click’ Reaction in Conjunction with Diazeniumdiolate Chemistry: Developing High-Load Nitric Oxide Donors

[Image: see text] The use of Cu(I)-catalyzed ‘click’ reactions of alkyne-substituted diazeniumdiolate prodrugs with bis- and tetrakisazido compounds is described. The ‘click’ reaction for the bis-azide using CuSO(4)/Na-ascorbate predominantly gave the expected bis-triazole. However, CuI/diisopropyle...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Oladeinde, Oyebola A., Hong, Sam Y., Holland, Ryan J., Maciag, Anna E., Keefer, Larry K., Saavedra, Joseph E., Nandurdikar, Rahul S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945422/
https://ncbi.nlm.nih.gov/pubmed/20812718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101645k
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