Insulin-like Signaling Determines Survival During Stress via Post Transcriptional Mechanisms in C. elegans

The insulin-like signaling (ILS) pathway regulates metabolism and is known to modulate adult lifespan in C. elegans. Altered stress responses and resistance to a wide range of stressors are also associated with changes in ILS and contribute to enhanced longevity. The transcription factors DAF-16 and...

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Главные авторы: McColl, Gawain, Rogers, Aric N., Alavez, Silvestre, Hubbard, Alan E., Melov, Simon, Link, Christopher D., Bush, Ashley I., Kapahi, Pankaj, Lithgow, Gordon J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945254/
https://ncbi.nlm.nih.gov/pubmed/20816092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.08.004
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