Inhibition of TIR Domain Signaling by TcpC: MyD88-Dependent and Independent Effects on Escherichia coli Virulence

Toll-like receptor signaling requires functional Toll/interleukin-1 (IL-1) receptor (TIR) domains to activate innate immunity. By producing TIR homologous proteins, microbes inhibit host response induction and improve their own survival. The TIR homologous protein TcpC was recently identified as a v...

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Detalhes bibliográficos
Main Authors: Yadav, Manisha, Zhang, Jingyao, Fischer, Hans, Huang, Wen, Lutay, Nataliya, Cirl, Christine, Lum, Josephine, Miethke, Thomas, Svanborg, Catharina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944809/
https://ncbi.nlm.nih.gov/pubmed/20886104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001120
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