Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli

The Toll/IL-1 receptor (TIR) domains are crucial signaling modules during innate immune responses involving the Toll-like receptors (TLRs) and IL-1 receptor (IL-1R). Myeloid differential factor 88 (MyD88) is a central TIR domain-containing adapter molecule responsible for nearly all TLR-mediated sig...

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Main Authors: Snyder, Greg A., Cirl, Christine, Jiang, Jiansheng, Chen, Kang, Waldhuber, Anna, Smith, Patrick, Römmler, Franziska, Snyder, Nathaniel, Fresquez, Theresa, Dürr, Susanne, Tjandra, Nico, Miethke, Thomas, Xiao, Tsan Sam
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2013
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637702/
https://ncbi.nlm.nih.gov/pubmed/23569230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215770110
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