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Resampling and Editing of Mischarged tRNA Prior to Translation Elongation
Faithful translation of the genetic code depends on the GTPase EF-Tu delivering correctly charged aminoacyl-tRNAs to the ribosome for pairing with cognate codons. The accurate coupling of cognate amino acids and tRNAs by the aminoacyl-tRNA synthetases is achieved through a combination of substrate s...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944653/ https://ncbi.nlm.nih.gov/pubmed/19285947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.01.031 |
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