Stoichiometry of triple-sieve tRNA editing complex ensures fidelity of aminoacyl-tRNA formation

Aminoacyl-tRNA synthetases catalyze the attachment of cognate amino acids onto tRNAs. To avoid mistranslation, editing mechanisms evolved to maintain tRNA aminoacylation fidelity. For instance, while rejecting the majority of non-cognate amino acids via discrimination in the synthetic active site, p...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chen, Lin, Tanimoto, Akiko, So, Byung Ran, Bakhtina, Marina, Magliery, Thomas J, Wysocki, Vicki H, Musier-Forsyth, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
RNA Prot Comp
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344894/
https://ncbi.nlm.nih.gov/pubmed/30418624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1153
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