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Resampling and Editing of Mischarged tRNA Prior to Translation Elongation

Faithful translation of the genetic code depends on the GTPase EF-Tu delivering correctly charged aminoacyl-tRNAs to the ribosome for pairing with cognate codons. The accurate coupling of cognate amino acids and tRNAs by the aminoacyl-tRNA synthetases is achieved through a combination of substrate s...

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Detalhes bibliográficos
Main Authors: Ling, Jiqiang, So, Byung Ran, Yadavalli, Srujana S., Roy, Hervé, Shoji, Shinichiro, Fredrick, Kurt, Musier-Forsyth, Karin, Ibba, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944653/
https://ncbi.nlm.nih.gov/pubmed/19285947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.01.031
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