Lersivirine, a Nonnucleoside Reverse Transcriptase Inhibitor with Activity against Drug-Resistant Human Immunodeficiency Virus Type 1

The nonnucleoside reverse transcriptase inhibitors (NNRTIs) are key components of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus type 1 (HIV-1). A major problem with the first approved NNRTIs was the emergence of mutations in the HIV-1 reverse transcri...

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Bibliographische Detailangaben
Hauptverfasser: Corbau, Romuald, Mori, Julie, Phillips, Chris, Fishburn, Lesley, Martin, Alex, Mowbray, Charles, Panton, Wendy, Smith-Burchnell, Caroline, Thornberry, Adele, Ringrose, Heather, Knöchel, Thorsten, Irving, Steve, Westby, Mike, Wood, Anthony, Perros, Manos
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944613/
https://ncbi.nlm.nih.gov/pubmed/20660667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01455-09
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