Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production

Toxigenic Clostridium difficile strains produce two toxins (TcdA and TcdB) during the stationary phase of growth and are the leading cause of antibiotic-associated diarrhea. C. difficile isolates of the molecular type NAP1/027/BI have been associated with severe disease and hospital outbreaks worldw...

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Main Authors: Merrigan, Michelle, Venugopal, Anilrudh, Mallozzi, Michael, Roxas, Bryan, Viswanathan, V. K., Johnson, Stuart, Gerding, Dale N., Vedantam, Gayatri
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Molecular Biology of Pathogens
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944552/
https://ncbi.nlm.nih.gov/pubmed/20675495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00445-10
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