Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production

Toxigenic Clostridium difficile strains produce two toxins (TcdA and TcdB) during the stationary phase of growth and are the leading cause of antibiotic-associated diarrhea. C. difficile isolates of the molecular type NAP1/027/BI have been associated with severe disease and hospital outbreaks worldw...

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Detalhes bibliográficos
Main Authors: Merrigan, Michelle, Venugopal, Anilrudh, Mallozzi, Michael, Roxas, Bryan, Viswanathan, V. K., Johnson, Stuart, Gerding, Dale N., Vedantam, Gayatri
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Molecular Biology of Pathogens
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944552/
https://ncbi.nlm.nih.gov/pubmed/20675495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00445-10
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