Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production

Toxigenic Clostridium difficile strains produce two toxins (TcdA and TcdB) during the stationary phase of growth and are the leading cause of antibiotic-associated diarrhea. C. difficile isolates of the molecular type NAP1/027/BI have been associated with severe disease and hospital outbreaks worldw...

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Autores principales: Merrigan, Michelle, Venugopal, Anilrudh, Mallozzi, Michael, Roxas, Bryan, Viswanathan, V. K., Johnson, Stuart, Gerding, Dale N., Vedantam, Gayatri
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Molecular Biology of Pathogens
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944552/
https://ncbi.nlm.nih.gov/pubmed/20675495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00445-10
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