Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production

Toxigenic Clostridium difficile strains produce two toxins (TcdA and TcdB) during the stationary phase of growth and are the leading cause of antibiotic-associated diarrhea. C. difficile isolates of the molecular type NAP1/027/BI have been associated with severe disease and hospital outbreaks worldw...

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Bibliografiska uppgifter
Huvudupphovsmän: Merrigan, Michelle, Venugopal, Anilrudh, Mallozzi, Michael, Roxas, Bryan, Viswanathan, V. K., Johnson, Stuart, Gerding, Dale N., Vedantam, Gayatri
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2010
Ämnen:
Molecular Biology of Pathogens
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944552/
https://ncbi.nlm.nih.gov/pubmed/20675495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00445-10
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