Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling

Recent work has made it clear that oxidant systems interact. To investigate potential cross talk between NADPH oxidase (Nox) 1 upregulation in vascular smooth muscle and endothelial function, transgenic mice overexpressing Nox1 in smooth muscle cells (Tg(SMCnox1)) were subjected to angiotensin II (A...

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Hlavní autoři: Dikalova, Anna E., Góngora, María Carolina, Harrison, David G., Lambeth, J. David, Dikalov, Sergey, Griendling, Kathy K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944492/
https://ncbi.nlm.nih.gov/pubmed/20639222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00242.2010
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