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Inducible nitric oxide synthase gene deletion exaggerates MAPK-mediated cyclooxygenase-2 induction by inflammatory stimuli

Cyclooxygenase (COX)-2 and inducible nitric oxide (NO) synthase (iNOS) are responsive to a wide array of inflammatory stimuli, have been localized to vascular smooth muscle cells (SMCs), and are intimately linked to the progression of vascular disease, including atherosclerotic lesion formation. We...

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Detalhes bibliográficos
Main Authors: Lamon, Brian D., Upmacis, Rita K., Deeb, Ruba S., Koyuncu, Hilal, Hajjar, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944480/
https://ncbi.nlm.nih.gov/pubmed/20543082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00144.2010
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