Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice.

To investigate the role of apoE in hepatic uptake of chylomicron remnants, we studied chylomicron metabolism in transgenic mice overexpressing apoE in the liver. Plasma clearance of injected 125I-labeled human chylomicrons was fivefold faster in transgenic mice than in controls. Immunohistochemistry...

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Detalhes bibliográficos
Main Authors: Shimano, H, Namba, Y, Ohsuga, J, Kawamura, M, Yamamoto, K, Shimada, M, Gotoda, T, Harada, K, Yazaki, Y, Yamada, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC294368/
https://ncbi.nlm.nih.gov/pubmed/8182153
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