Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice.

To investigate the role of apoE in hepatic uptake of chylomicron remnants, we studied chylomicron metabolism in transgenic mice overexpressing apoE in the liver. Plasma clearance of injected 125I-labeled human chylomicrons was fivefold faster in transgenic mice than in controls. Immunohistochemistry...

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Dades bibliogràfiques

Publicat a:	J Clin Invest
Autors principals:	Shimano, H, Namba, Y, Ohsuga, J, Kawamura, M, Yamamoto, K, Shimada, M, Gotoda, T, Harada, K, Yazaki, Y, Yamada, N
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical Investigation 1994
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294368/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8182153/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117218
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