Rapid decay of unstable Leishmania mRNAs bearing a conserved retroposon signature 3′-UTR motif is initiated by a site-specific endonucleolytic cleavage without prior deadenylation

We have previously shown that the Leishmania genome possess two widespread families of extinct retroposons termed Short Interspersed DEgenerated Retroposons (SIDER1/2) that play a role in post-transcriptional regulation. Moreover, we have demonstrated that SIDER2 retroposons promote mRNA degradation...

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Detalhes bibliográficos
Main Authors: Müller, Michaela, Padmanabhan, Prasad K., Rochette, Annie, Mukherjee, Debdutta, Smith, Martin, Dumas, Carole, Papadopoulou, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943621/
https://ncbi.nlm.nih.gov/pubmed/20453029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq349
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