RNA secondary structure and nucleotide composition of the conserved hallmark sequence of Leishmania SIDER2 retroposons are essential for endonucleolytic cleavage and mRNA degradation

We have reported previously that Short Interspersed Degenerate Retroposons of the SIDER2 subfamily, largely located within 3'UTRs of Leishmania transcripts, promote rapid turnover of mRNAs through endonucleolytic cleavage within the highly conserved second tandem 79-nt hallmark sequence (79-nt...

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Publicat a:PLoS One
Autors principals: Azizi, Hiva, Romão, Tatiany P., Santos Charret, Karen, Padmanabhan, Prasad K., de Melo Neto, Osvaldo P., Müller-McNicoll, Michaela, Papadopoulou, Barbara
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509151/
https://ncbi.nlm.nih.gov/pubmed/28704426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180678
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