RNA secondary structure and nucleotide composition of the conserved hallmark sequence of Leishmania SIDER2 retroposons are essential for endonucleolytic cleavage and mRNA degradation

We have reported previously that Short Interspersed Degenerate Retroposons of the SIDER2 subfamily, largely located within 3'UTRs of Leishmania transcripts, promote rapid turnover of mRNAs through endonucleolytic cleavage within the highly conserved second tandem 79-nt hallmark sequence (79-nt...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Azizi, Hiva, Romão, Tatiany P., Santos Charret, Karen, Padmanabhan, Prasad K., de Melo Neto, Osvaldo P., Müller-McNicoll, Michaela, Papadopoulou, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509151/
https://ncbi.nlm.nih.gov/pubmed/28704426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180678
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