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Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation

A fundamental aspect of the biogenesis and function of eukaryotic messenger RNA is the quality control systems that recognize and degrade non-functional mRNAs. Eukaryotic mRNAs where translation termination occurs too soon (nonsense-mediated decay)1 or fails to occur (non-stop decay)2 are rapidly de...

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Bibliografische gegevens
Hoofdauteurs: Doma, Meenakshi K., Parker, Roy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839849/
https://ncbi.nlm.nih.gov/pubmed/16554824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04530
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