Identification of microRNAs and their Endonucleolytic Cleavaged target mRNAs in colorectal cancer

Abstract Background Colorectal cancer (CRC) ranks the third among the most common malignancies globally. It is well known that microRNAs (miRNAs) play vital roles in destabilizing mRNAs and repressing their translations in this disease. However, the mechanism of miRNA-induced mRNA cleavage remains t...

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Main Authors: Fangbin Zhou, Donge Tang, Yong Xu, Huiyan He, Yan Wu, Liewen Lin, Jun Dong, Wenyong Tan, Yong Dai
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-03-01
Colecção:BMC Cancer
Assuntos:
microRNA
Colorectal Cancer
High-throughput small RNA sequencing
Degradome sequencing
Endonucleolytic cleavage
Acesso em linha:http://link.springer.com/article/10.1186/s12885-020-06717-4
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