Evaluation of Histone Deacetylases as Drug Targets in Huntington’s Disease models: Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell model.

The family of histone deacetylases (HDACs) has recently emerged as important drug targets for treatment of slow progressive neurodegenerative disorders, including Huntington’s disease (HD). Broad pharmaceutical inhibition of HDACs has shown neuroprotective effects in various HD models. Here we exami...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Quinti, Luisa, Chopra, Vanita, Rotili, Dante, Valente, Sergio, Amore, Allison, Franci, Gianluigi, Meade, Sarah, Valenza, Marta, Altucci, Lucia, Maxwell, Michele M., Cattaneo, Elena, Hersch, Steven, Mai, Antonello, Kazantsev, Aleksey
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Huntington Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943247/
https://ncbi.nlm.nih.gov/pubmed/20877454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1172
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados