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Nuclear Role of WASp in the Pathogenesis of Dysregulated T(H)1 Immunity in Human Wiskott-Aldrich Syndrome
The clinical symptomatology in the X-linked Wiskott-Aldrich syndrome (WAS), a combined immunodeficiency and autoimmune disease resulting from WAS protein (WASp) deficiency, reflects the underlying coexistence of an impaired T helper 1 (T(H)1) immunity alongside intact T(H)2 immunity. This suggests a...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943146/ https://ncbi.nlm.nih.gov/pubmed/20574068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000813 |
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