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Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding
Flap endonuclease 1 (FEN1), a structure-specific endo- and exo- nuclease, exhibits multiple functions that determine essential biological processes, such as cell proliferation and cell death. As such, the enzyme must be precisely regulated in order to execute each of its functions with the right tim...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943039/ https://ncbi.nlm.nih.gov/pubmed/20729856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.422 |
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