Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development

Flap endonuclease 1 (FEN1) phosphorylation is proposed to regulate the action of FEN1 in DNA repair as well as Okazaki fragment maturation. However, the biologic significance of FEN1 phosphorylation in response to DNA damage remains unknown. Here, we report an in vivo role for FEN1 phosphorylation,...

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Vydáno v:FASEB J
Hlavní autoři: Zhou, Lina, Dai, Huifang, Wu, Jian, Zhou, Mian, Yuan, Hua, Du, Juan, Yang, Lu, Wu, Xiwei, Xu, Hong, Hua, Yuejin, Xu, Jian, Zheng, Li, Shen, Binghui
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2017
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161519/
https://ncbi.nlm.nih.gov/pubmed/27694478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600631R
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