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Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding
Flap endonuclease 1 (FEN1), a structure-specific endo- and exo- nuclease, exhibits multiple functions that determine essential biological processes, such as cell proliferation and cell death. As such, the enzyme must be precisely regulated in order to execute each of its functions with the right tim...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943039/ https://ncbi.nlm.nih.gov/pubmed/20729856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.422 |
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