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Dansylation of unactivated alcohols for improved mass spectral sensitivity and application to analysis of cytochrome P450 oxidation products in tissue extracts
Chemical derivatization is useful for improving the ionization characteristics of poorly or non-ionizable analytes in liquid chromatography-mass spectrometry (LC-MS). Dansyl chloride has been widely used as a derivatizing reagent for fluorescence detection and for facilitating the MS detection of ph...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941762/ https://ncbi.nlm.nih.gov/pubmed/20795636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac1015497 |
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