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Characterizing Proteins of Unknown Function: Orphan Cytochrome P450 Enzymes as a Paradigm

With the rapid completion of genomic sequences of organisms today, we have far more gene products than functions we can ascribe. A number of experimental strategies have been developed and applied, both in vitro and in vivo, to put functions to these orphan proteins. The “deorphanization” of human a...

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Autori principali: Guengerich, F. Peter, Tang, Zhongmei, Salamanca-Pinzón, S. Giovanna, Cheng, Qian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Pharmacology and Experimental Therapeutics 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895278/
https://ncbi.nlm.nih.gov/pubmed/20539034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mi.10.3.6
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