Unexpected Role of the Copper Transporter ATP7A in PDGF-Induced Vascular Smooth Muscle Cell Migration

RATIONALE: Copper, an essential nutrient, has been implicated in vascular remodeling and atherosclerosis with unknown mechanism. Bioavailability of intracellular copper is regulated not only by the copper importer CTR1, but also by the copper exporter ATP7A (Menke ATPase) whose function is achieved...

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Bibliografiska uppgifter
Huvudupphovsmän: Ashino, Takashi, Sudhahar, Varadarajan, Urao, Norifumi, Oshikawa, Jin, Chen, Gin-Fu, Wang, Huan, Huo, Yuqing, Finney, Lydia, Vogt, Stefan, McKinney, Ronald D., Maryon, Edward B., Kaplan, Jack H., Ushio-Fukai, Masuko, Fukai, Tohru
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941562/
https://ncbi.nlm.nih.gov/pubmed/20671235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.225334
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