Unexpected Role of the Copper Transporter ATP7A in PDGF-Induced Vascular Smooth Muscle Cell Migration

RATIONALE: Copper, an essential nutrient, has been implicated in vascular remodeling and atherosclerosis with unknown mechanism. Bioavailability of intracellular copper is regulated not only by the copper importer CTR1, but also by the copper exporter ATP7A (Menke ATPase) whose function is achieved...

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Autores principales: Ashino, Takashi, Sudhahar, Varadarajan, Urao, Norifumi, Oshikawa, Jin, Chen, Gin-Fu, Wang, Huan, Huo, Yuqing, Finney, Lydia, Vogt, Stefan, McKinney, Ronald D., Maryon, Edward B., Kaplan, Jack H., Ushio-Fukai, Masuko, Fukai, Tohru
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941562/
https://ncbi.nlm.nih.gov/pubmed/20671235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.225334
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