Copper Transporter ATP7A Protects Against Endothelial Dysfunction in Type 1 Diabetic Mice by Regulating Extracellular Superoxide Dismutase

Oxidative stress and endothelial dysfunction contribute to vascular complication in diabetes. Extracellular superoxide dismutase (SOD3) is one of the key antioxidant enzymes that obtains copper via copper transporter ATP7A. SOD3 is secreted from vascular smooth muscles cells (VSMCs) and anchors at t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sudhahar, Varadarajan, Urao, Norifumi, Oshikawa, Jin, McKinney, Ronald D., Llanos, Roxana M., Mercer, Julian F.B., Ushio-Fukai, Masuko, Fukai, Tohru
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2013
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806617/
https://ncbi.nlm.nih.gov/pubmed/23884884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1228
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