Copper transporter ATP7A interacts with IQGAP1, a Rac1 binding scaffolding protein: role in PDGF-induced VSMC migration and vascular remodeling

Vascular smooth muscle cell (VSMC) migration contributes to neointimal formation after vascular injury. We previously demonstrated that copper (Cu) transporter ATP7A is involved in platelet-derived growth factor (PDGF)-induced VSMC migration in a Cu- and Rac1-dependent manner. The underlying mechani...

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Pubblicato in:Am J Physiol Cell Physiol
Autori principali: Ashino, Takashi, Kohno, Takashi, Sudhahar, Varadarajan, Ash, Dipankar, Ushio-Fukai, Masuko, Fukai, Tohru
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336942/
https://ncbi.nlm.nih.gov/pubmed/30257103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00230.2018
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