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Enhancement of antigen-specific Treg vaccination in vivo

The conversion of naive T cells into Treg can be achieved in vivo by delivery of antigen under subimmunogenic conditions. Here we have examined several drugs for their ability to enhance the conversion process in vivo and have found that the rapamycin analog everolimus potently enhances Treg convers...

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Detalhes bibliográficos
Main Authors: Daniel, Carolin, Wennhold, Kerstin, Kim, Hye-Jung, von Boehmer, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941325/
https://ncbi.nlm.nih.gov/pubmed/20805478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007422107
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