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Enhancement of antigen-specific Treg vaccination in vivo

The conversion of naive T cells into Treg can be achieved in vivo by delivery of antigen under subimmunogenic conditions. Here we have examined several drugs for their ability to enhance the conversion process in vivo and have found that the rapamycin analog everolimus potently enhances Treg convers...

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Autori principali: Daniel, Carolin, Wennhold, Kerstin, Kim, Hye-Jung, von Boehmer, Harald
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941325/
https://ncbi.nlm.nih.gov/pubmed/20805478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007422107
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