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Enhancement of antigen-specific Treg vaccination in vivo

The conversion of naive T cells into Treg can be achieved in vivo by delivery of antigen under subimmunogenic conditions. Here we have examined several drugs for their ability to enhance the conversion process in vivo and have found that the rapamycin analog everolimus potently enhances Treg convers...

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Bibliographic Details
Main Authors: Daniel, Carolin, Wennhold, Kerstin, Kim, Hye-Jung, von Boehmer, Harald
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941325/
https://ncbi.nlm.nih.gov/pubmed/20805478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007422107
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