Wordt geladen...
Instability of Helios-deficient Tregs is associated with conversion to a T-effector phenotype and enhanced antitumor immunity
Expression of the transcription factor Helios by Tregs ensures stable expression of a suppressive and anergic phenotype in the face of intense inflammatory responses, whereas Helios-deficient Tregs display diminished lineage stability, reduced FoxP3 expression, and production of proinflammatory cyto...
Bewaard in:
| Gepubliceerd in: | Proc Natl Acad Sci U S A |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2016
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4896716/ https://ncbi.nlm.nih.gov/pubmed/27185917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604765113 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|