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Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain
During viral replication, herpesviruses package their DNA into the procapsid by means of the terminase protein complex. In human cytomegalovirus (herpesvirus 5), the terminase is composed of subunits UL89 and UL56. UL89 cleaves the long DNA concatemers into unit-length genomes of appropriate length...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941324/ https://ncbi.nlm.nih.gov/pubmed/20805464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007144107 |
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