Structure-Driven Discovery of α,γ-Diketoacid Inhibitors Against UL89 Herpesvirus Terminase

[Image: see text] Human cytomegalovirus (HCMV) is an opportunistic pathogen causing a variety of severe viral infections, including irreversible congenital disabilities. Nowadays, HCMV infection is treated by inhibiting the viral DNA polymerase. However, DNA polymerase inhibitors have several drawba...

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Bibliografiska uppgifter
I publikationen:ACS Omega
Huvudupphovsmän: Bongarzone, Salvatore, Nadal, Marta, Kaczmarska, Zuzanna, Machón, Cristina, Álvarez, Mercedes, Albericio, Fernando, Coll, Miquel
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2018
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645139/
https://ncbi.nlm.nih.gov/pubmed/31458978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01472
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